VECTR enhances virtual crossmatching by integrating epitope and amino acid analysis for assisting in organ allocation and for better understanding antibody reactivity profiles.

Are you considering epitope analysis to improve transplant outcomes as well as find compatible matches to  your highly sensitized patients?

Are currently available sources too laborious and cumbersome?

Key Features of VECTR

  • Database-independent application that can connect to any LIMS database for data retrieval and analysis

  • Uses a top-down analysis approach, using eplets calculated from high  resolution typing and/or antigen data

  • Uses the epitope list from HLA Matchmaker, a commonly used database for  epitope matching

  • Detects eplets based on adjustable LSA cutoff values 

  • Provides a graphical representation of LSA reactivity for each patient

  • Displays records of sensitization history which are also incorporated in the  reactivity graphs for easier visual identification

• Designed to populate the following data based on the transplant type:

        • Donor specific antigens 

        • Donor specific eplets

        • Antibody reactivity permissible alleles

        • Permissible typing eplets 

  • Identifies the eplet reactivity for each patient using historical data with no  restriction on the number of time points

  • Expand the available Luminex bead panel by identifying the most immunogenically similar surrogate bead

  • Assess the risk of De-Novo DSA formation between patient and donor pairs instantly using configurable and adjustable cutoffs